Publications

(140) Diastereoselective Additions of Allylmetal Reagents to Free and Protected syn-α, β-Dihydroxyketones Enable Efficient Synthetic Routes to Methyl Trioxacarcinoside A
Daniel J. Smaltz, Jakub Švenda, and Andrew G. Myers
Organic Letters. 2012, 14 (7), 1812. Link to pdf

(139) Pseudoephenamine: A Practical Chiral Auxiliary for Asymmetric Synthesis.
Marvin R. Morales, Kevin T. Mellem, and Andrew G. Myers
Angewandte Chemie, International Edition. Published online. link to early view

(138) A Short and Efficient Synthetic Route to Methyl α-Trioxacarcinoside B and Anomerically Activated Derivatives.
Thomas Magauer and Andrew G. Myers
Organic Letters. 2011, 13 (20), 5584. Link to pdf

(137) Scalable Synthesis of Enantiomerically Pure syn-2,3-Dihydroxybutyrate by Sharpless Asymmetric Dihydroxylation of p-Phenylbenzyl Crotonate.
Daniel J. Smaltz and Andrew G. Myers
Journal of Organic Chemistry. 2011, 76 (20), 8554. Link to pdf

(136) Methodological Advances Permit the Stereocontrolled Construction of Diverse Fully Synthetic Tetracyclines Containing an All-Carbon Quaternary Center at Position C5a.
Peter M. Wright and Andrew G. Myers
Tetrahedron. 2011, 67 (51), 9853. Link to pdf

(135) A Versatile Synthesis of Substituted Isoquinolines.
Chong Si and Andrew G. Myers
Angewandte Chemie, International Edition. 2011, 50 (44), 10409. Link to pdf

(134)
Storable Arylpalladium(II) Reagents for Alkene Labeling in Aqueous Media.
Rebecca Lee Simmons, Robert Yu, and Andrew G. Myers
Journal of the American Chemical Society. 2011, 133 (40), 15797. Link to pdf

(133)
A Practical, Convergent Route to the Key Precursor to the Tetracycline Antibiotics.
David Kummer, Derun Li, Amelie Dion, and Andrew G. Myers
Chemical Science. 2011, 2 (9), 1710. Link to pdf

(132) A Multiply Convergent Platform for the Synthesis of Trioxacarcins.
Jakub Svenda, Nick Hill, and Andrew G. Myers
PNAS. 2011, 108 (17) 6709. Link to pdf

(131) Synthesis of Cortistatins A, K, J, and L.
Alec Flyer, Chong Si, and Andrew G. Myers
Nature Chemistry. 2010, 2, 886 download pdf

(130) Anti-Selective Epoxidation of Methyl α-Methylene-β-
tert-butyldimethyl-siloxycarboxylate Esters. Evidence for Stereospecific Oxygen Atom Transfer in a Nucleophilic Epoxidation Process.
Jakub Svenda and Andrew G. Myers
Org. Lett. 2009, 11, 2437 download pdf

(129) A Method for the Preparation of Differentiated trans-1,2-Diol Derivatives with Enantio- and Diastereocontrol.
Sang Min Lim, Nicholas Hill and Andrew G. Myers
J. Am. Chem. Soc. 2009, 131, 5763 download pdf

(128) A Robust Platform for the Synthesis of New Tetracycline Antibiotics.
Cuixiang Sun, Qui Wang, Jason D. Brubaker, Peter M. Wright, Christian D. Lerner, Kevin Noson, Mark Charest, Dionicio R. Siegel, Yi-Ming Wang and Andrew G. Myers
J. Am. Chem. Soc. 2008, 130, 17913 download pdf

(127) Stereocontrolled Alkylative Construction of Quaternary Carbon Centers.
David A. Kummer, William J. Chain, Marvin R. Morales, Olga Quiroga and Andrew G. Myers
J. Am. Chem. Soc. 2008, 130, 13231 download pdf

(126) The Natural Product Avrainvillamide Binds to the Oncoprotein Nucleophosmin.
Jeremy E. Wulff, Romain Siegrist and Andrew G. Myers
J. Am. Chem. Soc. 2007,129, 14444 download pdf

(125) A Practical, Enantioselective Synthetic Route to a Key Precursor to the Tetracycline Antibiotics.
Jason D. Brubaker and Andrew G. Myers
Org. Lett. 2007, 19, 3523 download pdf

(124) Synthesis of L-Kedarosamine in Protected Form and Its Efficient Incorporation into an Advanced Intermediate to Kedarcidin Chromophore.
Feng Ren, Philip C. Hogan, Alan J. Anderson, and Andrew G. Myers
Org. Lett. 2007, 9, 1923 download pdf

(123) Kedarcidin Chromophore-Synthesis of its Proposed structure and Evidence for a Streochemical Revision.
Feng Ren, Philip C. Hogan, Alan J. Anderson, and Andrew G. Myers
J. Am. Chem. Soc. 2007, 129, 5381 download pdf

(122) Evidence for the Rapid Conversion of Stephacidin B into the Electrophilic Monomer Avrainvillamide in Cell Culture.
Jeremy E. Wulff, Seth B. Herzon, Romain Siegrist and Andrew G. Myers
J. Am. Chem. Soc. 2007, 129, 4898 download pdf

(121) A Convenient, NMR-Based Method for the Analysis of Diastereomeric Mixtures of Pseudoephedrine Amides.
William J. Chain and Andrew G. Myers
Org. Lett. 2007, 9, 355 download pdf

(120) Efficient Transamidation of Primary Carboxamides by in Situ Activation with N,N-Dialkylformamide Dimethyl Acetals.
Thomas A. Dineen, Matthew A. Zajac and Andrew G. Myers
J. Am. Chem. Soc. 2006, 128, 16406 download pdf

(119) Enantioselective Synthesis of N1999A2.
Nan Ji, Hardwin O'Dowd, Brad M. Rosen and Andrew G. Myers
J. Am. Chem. Soc. 2006, >128, 14825 download pdf

(118) Evaluation of Antitumor Properties of Novel Saframycin Analogs in Vitro and in Vivo.
Jeffry R. Spencer, Martin Sendzik, Jason Oeh, Peter Sabbatini, Stacie A. Dalrymple, Catherine Magill, Hyunjin M. Kim, Penglie Zhang, Neil Squires, Katherine G. Moss, Juthamas Sukbuntherng, Doris Graupe, John Eksterowicz, Peter R. Young, Andrew G. Myers and Michael J. Green
Bioorg. Med. Chem. Lett. 2006, 16, 4884 download pdf

(117) Synthesis of (-)-Quinocarcin by Directed Condensation of a-Amino aldehydes.
Soojin Kwon and Andrew G. Myers
J. Am. Chem. Soc. 2005, 127, 16796 download pdf

(116) Use of Lithium Hexafluoroisopropoxide as a Mild Base for Horner-Wadsworth-Emmons Olefination of Epimerizable Aldehydes.
Landy K. Blasdel and Andrew G. Myers
Org. Lett. 2005, 7, 4281 download pdf

(115) Synthesis of (–)-Tetracycline.
Mark G. Charest, Dionicio R. Siegel and Andrew G. Myers
J. Am. Chem. Soc. 2005, 127, 8292 download pdf

(114) On the Mechanism of the Palladium(II)-Catalyzed Decarboxylative Olefination of Arene Carboxylic Acids. Crystallographic Characterization of non-Phosphine Palladium(II) Intermediates and Observation of their Stepwise Transformation in Heck-like Processes.
Daisuke Tanaka, Stuart P. Romeril and Andrew G. Myers
J. Am. Chem. Soc.2005, 10323 download pdf

(113) Enantioselective Synthesis of Stephacidin B.
Seth B. Herzon and Andrew G. Myers
J. Am. Chem. Soc. 2005, 127, 5342 download pdf

(112) A Convergent Enantioselective Route to Structurally Diverse 6-Deoxytetracycline Antibiotics.
Mark G. Charest, Christian D. Lerner, Jason D. Brubaker, Dionicio R. Siegel and Andrew G. Myers
Science 2005, 308, 395 download pdf

(111) A Method For the Rapid Synthesis of Highly Functionalized 2-Hydroxy-1-Naphthoates. Syntheses of the Naphthoic Acid Components of Neocarzinostatin Chromophore and N1999A2.
Nan Ji, Brad M. Rosen, and Andrew G. Myers
Org Lett. 2004, 6, 4551 download pdf

(110) A General Procedure for the Esterification of Carboxylic Acids with Diazoalkanes Generated In Situ by the Oxidation of N-tert-Butyldimethylsilylhydrazones with (Difluoroiodo)benzene.
Michael E. Furrow and Andrew G. Myers
J. Am. Chem. Soc. 2004, 126, 12222 download pdf

(109) An Enantioselective, Modular, and General Route to the Cytochalasins: Synthesis of L-696,474 and Cytochalasin B.
Andrew M. Haidle and Andrew G. Myers
Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 12048 download pdf

(108) Efficient, Stereoselective Synthesis of trans-2,5-Disubstituted Morpholines.
Brian A. Lanman and Andrew G. Myers
Org. Lett. 2004, 6, 1045 download pdf

(107) Practical Procedures for the Preparation of N-tert-Butyldimethylsilylhydrazones and their Use in Modified Wolff–Kishner Reductions, and in the Synthesis of Vinyl Halides and gem-Dihalides.
Michael E. Furrow and Andrew G. Myers
J. Am. Chem. Soc. 2004, 126, 5440 download pdf

(106) Heck-type Arylation of 2-Cycloalken-1-ones with Arylpalladium Intermediates formed by Decarboxylative Palladation and by Aryl Iodide Insertion.
Andrew G. Myers and Daisuke Tanaka
Org. Lett. 2004, 6, 433 download pdf

(105) Synthetic and Theoretical Studies of Cyclobuta[1,2:3,4]dicyclopentene. Organocobalt Intermediates in the Construction of the Unsaturated Carbon Skeleton and Their Transformation into Novel Cobaltacyclic Complexes by C–C Insertion.
Andrew G. Myers, Miki Sogi, Michael A. Lewis and Stephen P. Arvedson
J. Org. Chem. 2004, 69, 2516 download pdf

(104) Identification of GAPDH as a Protein Target of the Saframycin Class of Natural Antiproliferative Agents.
Chengguo Xing, Jacob R. LaPorte, Joseph K. Barbay and Andrew G. Myers
Proc. Natl. Acad. Sci. U.S.A 2004, 101, 5862 download pdf

(103) Identification of a Novel Michael Acceptor Group for the Reversible Addition of Oxygen- and Sulfur-Based Nucleophiles. Synthesis and Reactivity of the 3-Alkylidene-3H-indole 1-Oxide Function of Avrainvillamide.
Andrew G. Myers and Seth B. Herzon
J. Am. Chem. Soc. 2003, 125, 12080 download pdf

(102) A Solid-Supported, Enantioselective Synthesis Suitable for the Rapid Preparation of Large Numbers of Diverse Structural Analogs of (–)-Saframycin. A.
Andrew G. Myers and Brian A. Lanman
J. Am. Chem. Soc. 2002, 44, 12969 download pdf

(101) Development of a Decarboxylative Palladation Reaction and its Use in a Heck-type Olefination of Arene Carboxylates.
Andrew G. Myers, Daisuke Tanaka and Michael Mannion
J. Am. Chem. Soc. 2002, 124, 11250 download pdf

(100) Lewis Acid Mediated Control of Allylic Epoxide Opening in Carbocyclization and Halide Addition Pathways.
Andrew G. Myers and Michael Siu
Tetrahedron 2002, 58, 6397 download pdf

(99) o-Nitrobenzenesulfonylhydrazide.
Andrew G. Myers, Mohammad Movassaghi
Encyclopedia of Reagents for Organic Synthesis 2003

(98) Enantioselective Synthesis of Terpestacin and Fusaproliferin; Clarification of Rotational Assignments
Andrew G. Myers, Michael Siu and Feng Ren
J. Am. Chem. Soc. 2002, 124, 4230 download pdf

(97) Evidence for Facile Atropisomerism and Simple (non-Nucleophilic) Biradical-Forming Cycloaromatization within Kedarcidin Chromophore Aglycon. Determination of the Associated Kinetic Barriers in Asna-bridged Systems.
Andrew G. Myers, Alexander R. Hurd and Philip C. Hogan
J. Am. Chem. Soc. 2002, 124, 4583 download pdf

(96) Enantioselective Synthesis of Kedarcidin Chromophore Aglycon in Differentially Protected form.
Andrew G. Myers, Philip C. Hogan, Alexander R. Hurd and Steven D. Goldberg
Angew. Chem. Int. Ed. Engl. 2002, 6, 2105 download pdf

(95) Transcriptional Response Pathways in a Yeast Strain Sensitive to Saframycin A and a More Potent Analog: Evidence for a Common Basis of Activity.
Alleyn T. Plowright, Scott E. Schaus and Andrew G. Myers
Chemistry and Biology 2002, 9, 607 download pdf

(94) Development of an Enantioselective Synthetic Route to Neocarzinostatin Chromophore and its use for Multiple Radioisotopic Incorporation.
Andrew G. Myers, Ralf Glatthar, Maryls Hammond, Phil Harrington, Elaine Y. Kuo, Jun Liang, Scott Schaus, Yusheng Wu and Jia-Ning Xiang
J. Am. Chem. Soc. 2002 124, 5380 download pdf

(93) Gene Transcription Analysis of S. cerevisiae Exposed to Neocarzinostatin Protein-Chromophore Complex Reveals Evidence of DNA Damage, a Potential Mechanism of Resistance, and Consequences of Prolonged Exposure.
Scott E. Schaus, Duccio Cavalieri and Andrew G. Myers
Proc. Natl. Acad. Sci. U.S.A 2001, 20, 11075 download pdf

(92) Pseudoephedrine.
Andrew G. Myers and Mark G. Charest
Electronic Encyclopedia of Reagents for Organic Synthesis 2001

(91) Synthesis of a Broad Array of Highly Functionalized, Enantiomerically Pure Cyclohexanecarboxylic Acid Derivatives by Microbial Dihydroxylation of Benzoic Acid and Subsequent Oxidative and Rearrangement Reactions.
Andrew G. Myers, Dionicio R. Siegel, Daniel J. Buzard and Mark G. Charest
Org. Lett. 2001, 3, 2923 download pdf

(90) Synthesis and Evaluation of Bishydroquinone Derivatives of (–)-Saframycin A. Identification of a Versatile Molecular Template Imparting Potent Antiproliferative Activity. Andrew G. Myers and Alleyn T. Plowright
J. Am. Chem. Soc. 2001, 123, 5115 download pdf

(89) Asymmetric Synthesis of Chiral Organofluorine Compounds. Use of Nonracemic Fluoroidoacetic Acid as a Practical Electrophile and its Application to the Synthesis of Monofluoro Hydroxyethylene Dipeptide Isosteres within a Novel Series of HIV Protease Inhibitors.
Andrew G. Myers, Joseph K. Barbay and Boyu Zhong
J. Am. Chem. Soc. 2001, 123, 7207 download pdf

(88) On the Inherent Instability of α-Amino α'-Fluoro Ketones.
Andrew G. Myers and Joseph K. Barbay
Org. Lett. 2000, 3, 425 download pdf

(87) Synthesis of C-Protected α-Amino Aldehydes of High Enantiomeric Excess from Highly Epimerizable N-Protected α-Amino Aldehydes.
Andrew G. Myers, Boyu Zhong, Daniel W. Kung, Mohammad Movassaghi, Brian A. Lanman and Soojin Kwon
Org. Lett. 2000, 2, 3337 download pdf

(86) One-Step Construction of the Pentacyclic Skeleton of Saframycin A from a "Trimer" of α-Amino Aldehydes.
Andrew G. Myers and Daniel W. Kung
Org. Lett. 2000, 2, 3019 download pdf

(85) Synthesis of the Kedarcidin Core Structure By a Transannular Cyclization Pathway.
Andrew G. Myers and Steven D. Goldberg
Angew. Chem. Int. Ed. Engl. 2000, 39, 2732 download pdf

(84) Observations Concerning the Existence and Reactivity of Free α-Amino Aldehydes as Chemical Intermediates; Evidence for Epimerization-Free Adduct Formation with Various Nucleophiles.
Andrew G. Myers, Daniel W. Kung, and Boyu Zhong
J. Am. Chem. Soc. 2000, 122, 3236 download pdf

(83) Synthesis of Highly Epimerizable N-Protected α-Amino Aldehydes of High Enantiomeric Excess.
Andrew G. Myers, Boyu Zhong, Mohammad Movassaghi, Daniel W. Kung, Brian A. Lanman and Soojin Kwon
Tetrahedron Lett. 2000, 41, 1359 download pdf

(82) Transformation of Pseudoephedrine Amides into Highly Enantiomerically Enriched Aldehydes, Alcohols, and Ketones.
Andrew G. Myers, Bryant H. Yang and Hou Chen
Org. Synth. 1999, 77, 29

(81) Synthesis and Diastereoselective Alkylation of Pseudoephedrine Amides.
Andrew G. Myers and Bryant H. Yang
Org. Synth. 1999, 77, 22

(80) A Concise, Stereocontrolled Synthesis of (–)- Saframycin A by the Directed Condensation of α-Amino Aldehyde Precursors.
Andrew G. Myers and Daniel W. Kung
J. Am. Chem. Soc. 1999, 121, 10828 download pdf

(79) Preparation of Chiral, C-Protected α-Amino Aldehydes of High Optical Purity and Their Use as Condensation Components in a Linear Synthesis Strategy.
Andrew G. Myers and Daniel W. Kung
J. Am. Chem. Soc. 1999, 121, 8401 download pdf

(78) Synthetic Replacement of the Methylamino Group of Neocarzinostatin Chromophore with Hydroxyl Prohibits Thiol Activation in Organic Solvents and Diminishes the Rate and Efficiency of Thiol-Promoted DNA Cleavage in Water.
Andrew G. Myers and Jun Liang
Tetrahedron Lett. 1999, 40, 5129 download pdf

(77) Preparation of (tert-Butyldimethylsilyl)allene (silane, (1,1-dimethylethyl) dimethyl-1,2-propadienyl-).
Andrew G. Myers and Bin Zheng
Org. Synth. 1998, 76, 178.

(76) Asymmetric Synthesis of α-Amino Acids by the Alkylation of Pseudoephedrine Glycinamide. Preparation of L-Allylglycine and N-Boc L-Allylglycine.
Andrew G. Myers and James L. Gleason
Org. Synth. 1998, 76, 57.

(75) Greatly Simplified Procedures for the Synthesis of α-Amino Acids by the Direct Alkylation of Pseudoephedrine Glycinamide Hydrate.
Andrew G. Myers, Patrick Schnider and Soojin Kwon
J. Org. Chem. 1999, 64, 3322 download pdf

(74) Highly Efficient Methodology for the Reductive Coupling of Aldehyde Tosylhydrazones with Alkyllithium Reagents.
Andrew G. Myers and Mohammad Movassaghi
J. Am. Chem. Soc. 1998, 120, 8891 download pdf

(73) Concise Synthesis of the Bicyclic Core of the Chromoprotein Antibiotics Kedarcidin and Neocarzinostatin by Transannular Reductive Cyclization of a Tetrayne Precursor.
Andrew G. Myers and Steven D. Goldberg
Tetrahedron Lett. 1998, 39, 9633 download pdf

(72) Total Synthesis of (+)-Neocarzinostatin Chromophore.
Andrew G. Myers, Jun Liang, Marlys Hammond, Philip Harrington, Yusheng Wu, and Elaine Kuo
J. Am. Chem. Soc. 1998, 120, 5319 download pdf

(71) Practical Methodology for the Asymmetric Synthesis of Organofluorine Compounds.
Andrew G. Myers, Lydia McKinstry, Joseph K. Barbay and James L. Gleason
Tetrahedron Lett. 1998, 39, 1335 download pdf

(70) Synthesis of Tertiary Alkyl Fluoride Centers by Asymmetric C-C(F) Bond Formation.
Andrew G. Myers, Lydia McKinstry and James L. Gleason
Tetrahedron Lett. 1997, 38, 7037 download pdf

(69) Mechanistic Studies of the Free-Radical Fragmentation of Monoalkyl Diazenes.
Andrew G. Myers, Mohammad Movassaghi and Bin Zheng
Tetrahedron Lett. 1997, 38, 6569 download pdf

(68) Preparation of the Reagent o-Nitrobenzenesulfonylhydrazine.
Andrew G. Myers, Bin Zheng and Mohammad Movassaghi
J. Org. Chem. 1997, 62, 7507 download pdf
 
(67) A Single-Step Process for the Reductive Deoxygenation of Unhindered Alcohols.
Andrew G. Myers, Mohammad Movassaghi and Bin Zheng
J. Am. Chem. Soc. 1997, 119, 8572 download pdf

(66) Synthesis of the Naphthoic Acid Component of Kedarcidin Chromophore by Routes Employing Photochemical and Thermal Electrocyclic Ring Closure Reactions.
Andrew G. Myers and Yoshiaki Horiguchi
Tetrahedron Lett. 1997, 38, 4363 download pdf

(65) Pseudoephedrine as a Practical Chiral Auxiliary for the Synthesis of Highly Enantiomerically Enriched Carboxylic Acids, Alcohols, Aldehydes, and Ketones.
Andrew G. Myers, Bryant H. Yang, Hou Chen, Lydia McKinstry, David J. Kopecky and James L. Gleason
J. Am. Chem. Soc. 1997, 119, 6496 download pdf

(64) A Convergent Synthetic Route to (+)-Dynemicin A and Analogs of Wide Structural Variability.
Andrew G. Myers, Norma J. Tom, Mark E. Fraley, Scott B. Cohen and David J. Madar
J. Am. Chem. Soc. 1997, 119, 6072 download pdf

(63) Enzymatic Activation of DNA Cleavage by Dynemicin A and Synthetic Analogs.
Andrew G. Myers, Scott B. Cohen, Michael E. Kort and Norma J. Tom
Biochemistry 1997, 36, 3903 download pdf

(62) Asymmetric Synthesis of 1,3-Dialkyl-Substituted Carbon Chains of any Stereochemical Configuration by an Iterable Process.
Andrew G. Myers, Bryant H. Yang, Hou Chen and David J. Kopecky
Synlett. 1997, 36, 457 download pdf

(61) A Comparison of DNA Cleavage by Neocarzinostatin Chromophore and its Aglycone: Evaluating the Role of the Carbohydrate Residue.
Andrew G. Myers, Marlys Hammond and Michael Kort
J. Am. Chem. Soc. 1997, 119, 2965 download pdf

(60) Highly Practical Methodology for the Synthesis of D- and L-α-Amino Acids, N-Protected α-Amino Acids, and N-Methyl α-Amino Acids.
Andrew G. Myers, James L. Gleason, Taeyoung Yoon and Daniel W. Kung
J. Am. Chem. Soc. 1997, 119, 656 download pdf


(59) Three Dimensional Structure of Neocarzinostatin
K. Kim, Andrew G. Myers and D. Rees
Neocarzinostatin&emdash;Past, Present and Future of Anticancer Drug Development, Tokyo, 1997, 109 - 128.

(58) Enantioselective Synthesis of Neocarzinostatin Chromophore Aglycon.
Andrew G. Myers, Marlys Hammond, Yusheng Wu, Jia-Ning Xiang, Philip M. Harrington, and Elaine Y. Kuo
J. Am. Chem. Soc. 1996, 118, 10006 download pdf

(57) An Efficient Method for the Reductive Transposition of Allylic Alcohols.
Andrew G. Myers and Bin Zheng
Tetrahedron Lett. 1996, 37, 4841 download pdf

(56) Lithium Amidotrihydroborate, a Powerful New Reductant. Transformation of Tertiary Amides to Primary Alcohols.
Andrew G. Myers, Bryant Yang and David Kopecky
Tetrahedron Lett. 1996, 37, 3623 download pdf

(55) An Improved Preparation of Highly Enantiomerically Enriched (R)-(+)-4-tert-Butyldimethylsiloxy-2-cyclopenten-1-one.
Andrew G. Myers, Marlys Hammond and Yusheng Wu
Tetrahedron Lett. 1996, 37, 3083 download pdf

(54) New and Stereospecific Synthesis of Allenes in a Single Step from Propargylic Alcohols.
Andrew G. Myers and Bin Zheng
J. Am. Chem. Soc. 1996, 118, 4492 download pdf

(53) A New and Unusual Pathway for the Reaction of Neocarzinostatin Chromophore with Thiols. Revised Structure of the Protein-Directed Thiol Adduct.
Andrew G. Myers, Stephen P. Arvedson and Robert W. Lee
J. Am. Chem. Soc. 1996, 118, 4725 download pdf

(52) DNA Cleavage by an α,3-Dehydrotoluene Precursor Conjugated to a Minor Groove Binding Element.
Andrew G. Myers and Cynthia A. Parrish
Bioconjugate Chemistry 1996, 7, 322

(51) A Concise Synthesis of the Naphthoic Acid Component of Neocarzinostatin Chromophore Featuring a New Photocyclization Reaction.
Andrew G. Myers, Vijaya Subramanian and Marlys Hammond
Tetrahedron Lett. 1996, 37, 587 download pdf

(50) Practical Syntheses of Enantiomerically Enriched γ-Lactones and γ-Hydroxy Ketones by the Alkylation of Pseudoephedrine Amides with Epoxides and their Derivatives.
Andrew G. Myers and Lydia McKinstry
J. Org. Chem. 1996, 61, 2428 download pdf

(49) A Practical Synthesis of L-Azatyrosine.
Andrew G. Myers and James L. Gleason
J. Org. Chem. 1996, 61, 813 download pdf

(48) Synthesis of Highly Enantiomerically Enriched N-Boc-α-amino Ketones from Pseudoephedrine N-Boc-α-amino Acid Amides.
Andrew G. Myers and Taeyoung Yoon
Tetrahedron Lett. 1995, 36, 9429 download pdf

(47) Synthesis of Functionalized Enynes by Palladium/Copper-Catalyzed Coupling Reactions of Acetylenes with (Z)-2,3-Dibromopropenoic Acid Ethyl Ester: (Z)-2-Bromo-5-(trimethylsilyl)-2-penten-4-ynoic Acid Ethyl Ester.
Andrew G. Myers and Peter S. Dragovich
Org. Synth. 1995, 72, 104.

(46) A Practical Method for the Synthesis of D- or L-α-Amino Acids by the Alkylation of (+)- or (–)-Pseudoephedrine Glycinamide.
Andrew G. Myers, James L. Gleason and Taeyoung Yoon
J. Am. Chem. Soc. 1995, 117, 8488 download pdf

(45) A One-Step Synthesis of Pseudoephedrine Glycinamide, a Versatile Precursor for the Synthesis of α-Amino Acids.
Andrew G. Myers, Taeyoung Yoon and James L. Gleason
Tetrahedron Lett. 1995, 36, 4555 download pdf


(44) Insights into the Mechanism of DNA Cleavage by Dynemicin A as Revealed by DNA-Binding and -Cleavage Studies of Synthetic Analogs.
Andrew G. Myers, Scott B. Cohen, Norma J. Tom, David J. Madar and Mark E. Fraley
J. Am. Chem. Soc. 1995, 117, 7574 download pdf

(43) Synthesis of (+)-Dynemicin A and Analogs of Wide Structural Variability. Establishment of the Absolute Configuration of Natural Dynemicin A.
Andrew G. Myers, Mark E. Fraley, Norma J. Tom, Scott B. Cohen and David J. Madar
Chemistry and Biology 1995, 2, 33 download pdf

(42) Synthesis of (±)-7,8-Epoxy-4-basmen-6-one by a Transannular Cyclization Strategy.
Andrew G. Myers and Kevin R. Condroski
J. Am. Chem. Soc. 1995, 117, 3057 download pdf

(41) A Highly Convergent Route to Dynemicins of Wide Structural Variability. Enantioselective Synthesis of Quinone Imine Precursors to Natural and Nonnatural Dynemicins.
Andrew G. Myers, Mark E. Fraley and Norma J. Tom
J. Am. Chem. Soc. 1994, 116, 11556 download pdf

(40) The Use of Pseudoephedrine as a Practical Chiral Auxiliary for Asymmetric Synthesis.
Andrew G. Myers, Bryant H. Yang, Hou Chen and James L. Gleason
J. Am. Chem. Soc. 1994, 116, 9361
download pdf

(39) Synthetic Studies of the Tunicamycin Antibiotics. Preparation of (+)-Tunicaminyluracil, (+)-Tunicamycin V, and 5'-epi-Tunicamycin V.
Andrew G. Myers, David Y. Gin and Daniel H. Rogers
J. Am. Chem. Soc. 1994, 116, 4697 download pdf

(38) DNA Cleavage by Neocarzinostatin Chromophore. Establishing the Intermediacy of Chromophore-Derived Cumulene and Biradical Species and their Role in Sequence-Specific Cleavage.
Andrew G. Myers, Scott B. Cohen and Byoung-Mog Kwon
J. Am. Chem. Soc. 1994, 116, 1670 download pdf

(37) A Study of the Reaction of Calicheamicin γ1 with Glutathione in the Presence of Double-Stranded DNA.
Andrew G. Myers, Scott B. Cohen and Byoung-Mog Kwon
J. Am. Chem. Soc. 1994, 116, 1255 download pdf

(36) Crystal Structure of Neocarzinostatin, an Antitumor Protein-Chromophore Complex.
Kyoung-Hee Kim, Byoung-Mog Kwon, Andrew G. Myers and Douglas Rees
Science 1993, 262, 1042 download pdf

(35) Synthesis of (±)-7,8-Epoxy-4-basmen-6-one by a Transannular Cyclization Strategy.
Andrew G. Myers and Kevin R. Condroski
J. Am. Chem. Soc. 1993, 115, 7926 download pdf

(34) A Reaction Cascade Leading to 1,6-Didehydro[10]annulene 1,5-Dehydronaphthalene Cyclization Initiated by Thiol Addition.
Andrew G. Myers and Peter S. Dragovich
J. Am. Chem. Soc. 1993, 115, 7021 download pdf

(33) A Convergent Synthetic Route to the Tunicamycin Antibiotics. Synthesis of (+)-Tunicamycin V.
Andrew G. Myers, David Y. Gin and Daniel H. Rogers
J. Am. Chem. Soc. 1993, 115, 2036 download pdf
 
(32) Structure of a Syn Aldol Addition Product of Benzaldehyde and A Prolinol-Derived O-Silacyclopentyl Ketene N,O-Acetal.
Richard E. Marsh, William P. Schaefer, Susan E. Kephart and Andrew G. Myers
Acta Crystallogr. Sect. C: Cryst. Struct. Commun. 1993, 49, 185 download pdf

(31) Synthesis of 1,6-Didehydro[10]annulene. Observation of its Exceptionally Facile Rearrangement to Form the Biradical 1,5-Dehydronaphthalene.
Andrew G. Myers and Nathaniel S. Finney
J. Am. Chem. Soc. 1992, 114, 10986 download pdf

(30) Silicon-Directed Aldol Reactions. Rate Acceleration by Small Rings.
Andrew G. Myers, Susan E. Kephart and Hou Chen
J. Am. Chem. Soc. 1992, 114, 7922 download pdf

(29) Studies on the Thermal Generation and Reactivity of a Class of (σ,π)-1,4-Biradicals.
Andrew G. Myers, Peter S. Dragovich and Elaine Y. Kuo
J. Am. Chem. Soc. 1992, 114, 9369 download pdf

(28) Design and Synthesis of a System for Enediyne Formation by Anthraquinone Reductive Activation.
Andrew G. Myers and Peter S. Dragovich
J. Am. Chem. Soc. 1992, 114, 5859 download pdf

(27) Silicon-Directed Aldol Condensation. Evidence for a Pseudorotational Mechanism.
Andrew G. Myers, Katherine L. Widdowson and Paivi J. Kukkola
J. Am. Chem. Soc. 1992, 114, 2765 download pdf
 
(26) Structure of an 11-Membered Cyclic Silyl Enol Ether from Condensation of Methacrolein and a Pseudoephedrine-Derived O-Silyl Ketene N,O -Acetal.
William P. Schaefer, Vijaya Subramanian and Andrew G. Myers
Acta Crystallogr. Sect. C: Cryst. Struct. Commun. 1992, 48, 2090 download pdf

(25) Evidence for Aminoglycoside Participation in Thiol Activation of Neocarzinostatin Chromophore. Synthesis and Reactivity of the Epoxy Dienediyne Core.
Andrew G. Myers, Philip M. Harrington and Byoung-Mog Kwon
J. Am. Chem. Soc. 1992, 114, 1086 download pdf

(24) Structure of an Anti Aldol Addition Product of Benzaldehyde and a Pseudoephedrine-Derived O-Silyl Ketene N,O-Acetal.
Richard E. Marsh, William P. Schaefer, Katherine L. Widdowson and Andrew G. Myers
Acta Crystallogr. Sect. C: Cryst. Struct. Commun. 1992, 48, 1948 download pdf

(23) A Chiral N-Crotonyloxazolidinone Diels-Alder Adduct.

Richard E. Marsh, William P. Schaefer, Paivi J. Kukkola and Andrew G. Myers
Acta Crystallogr. Sect. C: Cryst. Struct. Commun. 1992, 48, 1622 download pdf

(22) Silicon Mediated Reductive Coupling of Aldehydes and Allylic Alcohols. A Stereoselective Synthesis of Tunicaminyluracil.
Andrew G. Myers, David Y. Gin and Katherine L. Widdowson
J. Am. Chem. Soc. 1991, 113, 9661 download pdf

(21) Structure of a Chiral Cyclopentanone Precursor in Neocarzinostatin Synthetic Studies, C20H21NO3S.H2O.

William P. Schaefer, Elaine Y. Kuo, Philip M. Harrington and Andrew G. Myers
Acta Crystallogr. Sect. C: Cryst. Struct. Commun. 1991, 47, 2578 download pdf

(20) Structures of Two Diastereomeric Aldol Products from a New Silicon-Directed Condensation.

William P. Schaefer, Katherine L. Widdowson and Andrew G. Myers
Acta Crystallogr. Sect. C: Cryst. Struct. Commun. 1991, 47, 2575 download pdf


(19) Enantioselective Synthesis of the Epoxydiyne Core of Neocarzinostatin Chromophore.
Andrew G. Myers, Philip M. Harrington and Elaine Y. Kuo
J. Am. Chem. Soc. 1991, 113, 694 download pdf

(18) A Silicon-Directed Aldol Condensation. Synthesis of Enantiomerically Pure Anti Aldols.
Andrew G. Myers and Katherine L. Widdowson
J. Am. Chem. Soc. 1990, 112, 9672 download pdf

(17) Direct Observation and Retro-ene Reaction of a Propargylic Diazene. Stereochemical Assignment of Monoalkyl Diazenes.
Andrew G. Myers and Nathaniel S. Finney
J. Am. Chem. Soc. 1990, 112, 9641 download pdf

(16) Stereoselective Synthesis of Olefins from Silylated Sulfonylhydrazones.
Andrew G. Myers and Paivi J. Kukkola
J. Am. Chem. Soc. 1990, 112, 8208 download pdf

(15) Design and Dynamics of a Chemically Triggered Reaction Cascade Leading to Biradical Formation at Subambient Temperature.
Andrew G. Myers and Peter S. Dragovich
J. Am. Chem. Soc. 1989, 111, 9130 download pdf

(14) Versatile Precursors for the Synthesis of Enynes and Enediynes.
Andrew G. Myers, Mian M. Alauddin, Mary Ann M. Fuhry, Peter S. Dragovich, Nathaniel S. Finney and Philip M. Harrington
Tetrahedron Lett. 1989, 30, 6997 download pdf

(13) Allene Synthesis from 2-Alkyn-1-ols.
Andrew G. Myers, Nathaniel S. Finney and Elaine Y. Kuo
Tetrahedron Lett. 1989, 30, 5747 download pdf

(12) Thermal Generation of a α,3-Dehydrotoluene from (Z)-1,2,4-Heptatrien-6-yne.
Andrew G. Myers, Elaine Y. Kuo and Nathaniel S. Finney
J. Am. Chem. Soc. 1989, 111, 8057 download pdf

(11) Evidence for Spontaneous, Low-Temperature Biradical Formation from a Highly Reactive Neocarzinostatin Chromophore-Thiol Conjugate.
Andrew G. Myers and Philip J. Proteau, J. Am.
Chem. Soc. 1989, 111, 1146 download pdf
 
(10) Direct Transformation of 2,3-Epoxy Alcohols into Hydroxy Carbonates Under Mildly Basic Conditions.
Andrew G. Myers and Katherine L. Widdowson
Tetrahedron Lett. 1988, 29, 6389 download pdf

(9) Mild Conditions for the Removal of Acid-Labile Protective Groups.
Andrew G. Myers, Mary Ann M. Fundy and Peter A. Lindstrom, Jr.
Tetrahedron Lett. 1988, 29, 5609 download pdf

(8) Stereochemical Assignment of Neocarzinostatin Chromophore. Structures of Neocarzinostatin Chromophore-Methyl Thioglycolate Adducts.
Andrew G. Myers, Philip J. Proteau and Tracy M. Handel
J. Am. Chem. Soc. 1988, 110, 7212 download pdf

(7) Proposed Structure of the Neocarzinostatin Chromophore-Methyl Thioglycolate Adduct; A Mechanism for the Nucleophilic Activation of Neocarzinostatin.
Andrew G. Myers
Tetrahedron Lett. 1987, 28, 4493 download pdf

(6) Simple Synthetic Route to the Limonoid System.
E.J. Corey, J. Gregory Reid, Andrew G. Myers and Robert W. Hahl
J. Am. Chem. Soc. 1986, 109, 918 download pdf

(5) Constitution of Antheridium-Inducing Factor of Anemia Phyllitidis.
E. J. Corey, Andrew G. Myers, Nobutaka Takahashi, Hisakazu Yamane and Helmut Schraudolf
Tetrahedron Lett. 1986, 27, 5083 download pdf

(4) Total Synthesis of (±)-Antheridium-Inducing Factor of the Fern Anemia phyllitidis. Clarification of Stereochemistry.

E. J. Corey and Andrew G. Myers
J. Am. Chem. Soc. 1985, 107, 5574 download pdf

(3) In Vivo Distribution and Activity of Aphidicolin on Dividing and Quiescent Cells.
S. Spadari, F. Focher, C. Kuenzle, E. J. Corey, Andrew G. Myers, N. Hardt and A. Rebuzzini
Antiviral Research 1985, 5, 93

(2) Efficient Synthesis and Intramolecular Cyclopropanation of Unsaturated Diazoacetic Esters.
E. J. Corey and Andrew G. Myers
Tetrahedron Lett. 1984, 25, 3559 download pdf

(1) Antibiotic X-14547A: Total Synthesis of the Right-Hand Half.

William R. Roush and Andrew G. Myers
J. Org. Chem. 1981, 46, 1509 download pdf

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Patents

1.
U.S. Patent No. 5,488,131, issued January 30, 1996. Andrew G. Myers. "Synthesis of Compounds with Predetermined Chirality"
2.
U.S. Letters Patent No. 5,760,237, issued June 2, 1998. Andrew G. Myers. "Synthesis of L-Azatryrosine Using Pseudoephedrine as as Chiral Auxiliary"
3.
U.S. Patent Application Serial No. 08/811,826. Andrew G. Myers. "Dynemicin Analogs"
4.
U.S. Patent No. 7,183,054. Andrew G. Myers. "Assay for Identifying Biological Targets of Polynucleotide-Binding Compounds"
5.
U.S. Patent No. 6,809,099, issued October 26, 2004. Andrew G. Myers. "Saframycins, Analogues and Uses Thereof"

Japanese Patent Application Serial No. 2002-543487. Andrew G. Myers. "Saframycin, Analogues and Uses Thereof"

U.S. Patent No. 7,122,549, issued October 17, 2006. Andrew G. Myers. "Saframycin, Analogues and Uses Thereof"

U.S. Patent Application Serial No. 11/582,526. Andrew G. Myers. "Saframycin, Analogues and Uses Thereof"

European Patent Application No. 019877338.9. Andrew G. Myers. "Synthesis of Saframycin, Analogues, and Uses Thereof"
6.
U.S. Patent Application Serial No. 11/133,789. Andrew G. Myers. "Synthesis of Tetracyclines and Analogues Thereof"

PCT International Application Serial No. US2005/17831. Andrew G. Myers. "Synthesis of Tetracyclines and Analogues Thereof"

European Patent Application No. 3864/KOLNP/2006. Andrew G. Myers. "Synthesis of Tetracyclines and Analogues Thereof"

PRC Patent Application No. 200580023494.4. Andrew G. Myers. "Synthesis of Tetracyclines and Analogues Thereof"

Australian Patent Application No. 2005244988. Andrew G. Myers. "Synthesis of Tetracyclines and Analogues Thereof"
7.
PCT International Application Serial No. US2006/009749, WO2006/102097. Andrew G. Myers. "Synthesis of Avrainvillamide, Stephacidin G, and Analogues Thereof"

U.S. National Phase Patent Application No. 11/908,901. Andrew G. Myers. "Synthesis of Avrainvillamide, Stephacidin G, and Analogues Thereof"

EPC Application Serial No. 06738771.2-1211-US2006009749. Andrew G. Myers. "Synthesis of Avrainvillamide, Stephacidin G, and Analogues Thereof"
8.
U.S. Patent Application No. 11/870,772. Andrew G. Myers. "Synthesis of Enone Intermediate"
9.
U.S. Patent Application No. 61/174,185. Andrew G. Myers. "Synthesis of Tetracyclines and Intermediates Thereto"