Chemistry 215 Handouts

Listed below are PDFs of the handouts used in Professor Myers' Chemistry 215 class, which is entitled, "Advanced Organic Chemistry: Synthesis of Complex Molecules." The handouts cover many essential reactions widely used in modern organic synthesis, and they are arranged according to the order in which they are covered in class.

• Reduction

• Oxidation

• Protective Groups – Silicon-Based Protection of the Hydroxyl Group

• Birch Reduction

• Asymmetric Alkylation of Enolates

• Asymmetric Allylation Reactions

• Magnesium Halogen Exchange

• Organolithium Reagents

• Lithium Halogen Exchange

• Directed Ortho Metalation

• Stille Reaction

• Suzuki Reaction

• Heck Rection

• Stereoselective-Directed Aldol Reaction

• Horner-Wadsworth-Emmons Olefination

• Sharpless Asymmetric Epoxidation Reaction

• Sharpless Asymmetric Dihydroxylation Reaction

• Jacobsen Asymmetric Epoxidation Reaction

• Shi Epoxidation

• Jacobsen Catalytic Epoxide-Opening Reaction

• Transformations of 2-3-Epoxy Alcohols

• The Noyori Asymmetric Hydrogenation Reaction

• Asymmetric Diels Alder Reaction

• The Olefin Metathesis Reaction